ncRNA name | STAT3 siRNA |
ncRNA Category | siRNA |
Disease name | retinoblastoma (RB) |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | qPCR, siRNA injection, microarray |
Expression pattern | associated |
Functional description | STAT3 inhibition by targeted siRNA suppresses the proliferation of retinoblastoma cells and the formation of in vivo orthotopic tumors. STAT3 siRNA effectively induces down-regulation of target genes of STAT3. |
PubMed ID | 25359779 |
Year | 2014 |
Title | STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters. |
Drug-related ncRNA | NO |
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